Treacher Collins Syndrome

Wichai Prasartritha, M.D.
Tiam Lawtiantong, M.D.
Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Bangkok. Thailand

Abstract We report one case of Treacher Collins syndrome. The inheritance pattern of this syndrome is autosomal dominant with variable expressivity. Major involvement occurs in those structures that derive from the first branchial arch, groove, and pouch which involved with abnormal ocular findings, lacrimal apparatus. The ear canals and pinnas are malformed. There are hypoplasia of mandible and maxilla, and there is a high frequency of associated high, arched palate or cleft palate.

Thai J Ophthalrnol 1988; 2 (2):83-85.