Chioroquine
Keratopathy
Patthanee
Samsen M.D*
Ngamkae Ruangvoravate
M.D.*
Yani Chiemchaisri M.D.*
Lek Parivisutti M.D.**
* Department of Ophthalmology,
Faculty of Medicine, Siriraj Hospital.
** Department of Medicine, Faculty
of Medicine, Siriraj Hospital.
Abstract One hundred and three patients receiving
chioroquine phosphate orally for either rheumatologic or dermatologic diseases
were examined. Keratopathy was found in twenty-nine patients (28.2%) varied
from Hudson-Stahli line to cornea verticillata.
There were no correlations
between keratopathy and age of the patients and cumulative dose of chloroquine,
but some correlations existed between the occurence of corneal deposits and
chloroquine retinopathy (p 0.02624). The incidence of keratopathy was significantly
high in patients with rheumatoid arthritis (40.7%).
Thai J Ophthalmol 1995 ; July-December 9(2):
167-173.
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