Spontaneous Regression of Retinoblastoma : A Case Report

Supaporn Tengtrisorn M.D.

Winyu Mitranant M.D.

Wasee Tulvatana M.D.

ABSTRACT : A 3 month old boy presented with rapidly ocular inflammation and hyphema. Three weeks after diagnosis of the retinoblastoma, the tumor spontaneously regressed without specific treatment. The eye was enucleated and sent to a pathologist and ophthalmic pathologist. Gross examination showed serious atrophy of the eyeball. Microscopic examination disclosed a large intraocular mass composed of multiple areas of fossilized tumor cells intervening with areas of cell necrosis and calcification. The final pathological findings in this young patients have been termed true spontaneous regression.

Thai J Ophthalmol 2000 ; July-December 14(2) : 183-188.

Key word : retinoblastoma, spontaneous regression, retinoma, retinocytoma.