Endophthalmitis Treatment with Local and Oral Antibiotics
Jutalai Tanterdtham, M.D.
Apichart Singalavanija, M.D.
Chakrapong Namatra, M.D.
Adisak Trinavarat, M.D.
Parapun Bamroongsuk, M.D.
*Department of Ophthalmology Faculty of Medicine, Siriraj Hospital

ABSTRACT : A research team studied the treatment of endophthalmitis post cataract extraction and intraocular lens implantation by administering intravitreal antibiotics, subconjunctival antibiotics, and topical antibiotics combined with an oral antibiotic (ofloxacin), without intravenous antibiotics, in 23 patients. Results were that this regimen of antibiotics controlled infection in the majority of cases (20 patients). In 3 patients, the infection could not be controlled, and vitrectomy was performed. Of the 20 patients responding to antibiotics the majority (14 patients) needed only one dose of intravitreal antibiotics. The other 6 patients needed 2 intravitreal doses to control infection. Three patients needed late vitrectomy (4 month after treatment) due to vitreal clouding. At 3 months follow up time visual acuity > 6/60 in 15 cases (65.25%), < 6/60 in 8 case (34.78%).

Thai J Ophthlamol 2004 : January – March 18(1) ; 27-34.